Automaxion has recently worked with a number of universities on applying our technology to Mechano-Chemistry which has resulted in the researchers being able to perform many more experiments in shorter time. The following are articles that have been published as a result of this cooperation.

(1) High throughput mechanochemistry: application to parallel synthesis of benzoxazines

For details, obtain the article by clicking this link.



We describe herein an unprecedented mechanochemical “parallel synthesis” of 3,4-dihydro-2H-benzo[e][1,3]oxazine derivatives via a one pot three component reaction. The new milling system uses a multiposition jar (variable sizes are possible), allowing for the processing of up to 12 samples simultaneously, leading to the formation of a fungicide and a building block for polymer preparation with higher throughput compared to standard milling devices.

Graphical abstract: High throughput mechanochemistry: application to parallel synthesis of benzoxazines
 Link to supplementary information (including experimental details) as a pdf.

(2) Processing and Investigation Methods in Mechanochemical Kinetics

For details, obtain the article by clicking this link.

Evelina Colacino, Maria Carta, Giorgio Pia, Andrea Porcheddu, Pier Carlo Ricci, and Francesco Delogu


The present work focuses on the challenges that emerge in connection with the kinetics of mechanically activated transformations. This is an important topics to comprehend to enable the full exploitation of mechanical processing in a broad spectrum of areas related to chemistry and materials science and engineering. Emerging challenges involve a number of facets regarding materials and material properties, working principles of ball mills and milling conditions, and local changes occurring in series in processed materials. Within this context, it is highly desirable to relate the nature and rate of observed mechanochemical transformations to individual collisions and then to the processes induced by mechanical stresses on the molecular scale.
Hence, it is necessary to characterize the milling regimes that can establish in ball mills regarding frequency and energy of collisions, map the relationship between milling dynamics and transformation kinetics, and obtain mechanistic information through proper time-resolved  investigations in situ. A few specific hints are provided in this respect.

Our Clients


Automaxion, L'Auvrairie, 50250 Varenguebec, France
NEW +33 2 50 69 33 08
This email address is being protected from spambots. You need JavaScript enabled to view it.

About Automaxion

Now based in France, Dr Bysouth gained his extensive experience working in the UK, The United States and The Netherlands for universities, multinationals and start-ups. He started his own company, Automaxion, to make his independent and innovative approach to laboratory research more broadly available.

Follow Us On: